Decoding BDNF-LTP Coupling in Cocaine Addiction
نویسندگان
چکیده
BDNF is a neurotrophic peptide that regulates synaptic plasticity. New work by Lu and coworkers in this issue of Neuron now identifies BDNF as a gatekeeper of synaptic and behavioral plasticity in cocaine sensitization. In the medial prefrontal cortex, upregulated BDNF facilitates LTP and contributes to neurobehavioral adaptations to psychostimulants.
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ورودعنوان ژورنال:
- Neuron
دوره 67 شماره
صفحات -
تاریخ انتشار 2010